Fellow winger Gabriel Martinelli is out with a hamstring injury and that has paved the way for his rival to come into the team.
The Belgian came off the bench at the weekend and scored the only goal of the game as the Gunners beat Everton at Goodison Park.
Mikel Arteta has made three changes from that win over Everton, though David Raya keeps his place in goal as Aaron Ramsdale once again has to settle for a place on the bench.
Kai Havertz comes into the midfield in place of Fabio Vieira, while Gabriel Jesus starts through the middle for the Gunners.
The Brazilian missed the start of the season with a knee injury but has confirmed that he is now fully fit.
“My knee is better,” he said. “It was unlucky and I had to do it (surgery) and now I am getting better. Now my knee is perfect. I have more rhythm. I am training, I am doing my best.”
Arsenal XI: Raya; White, Saliba, Gabriel, Zinchenko; Rice, Odegaard, Havertz; Saka, Jesus, Trossard
Subs: Ramsdale, Hein, Cedric, Kiwior, Tomiyasu, Jorginho, Vieira, Smith Rowe, Nketiah, Nelson, Elneny
Venue: Emirates Stadium
Referee: Felix Zwayer