BUZZ-Woodford Patient Capital Trust takes Prothena hit
** Shares (Berlin: DI6.BE - news) in Woodford Patient Capital Trust down 4.8 pct, second-biggest faller in the FTSE mid-cap index
** Stock hit by news key early stage pharma holding Prothena , in which the trust holds an 8.56 percent stake, to discontinue Pronto study
** Woodford Investment Management says also held a 2.67 percent stake in its Woodford Equity Income Fund and a 1.65 percent stake in its Woodford Income Focus Fund at end-Feb
** Fund manager Neil Woodford says trial results "undoubtedly a blow" after earlier being increasingly confident it would be successful
** Woodford says to work with company on strategy, points to rest of company's pipeline, technology platform, strong balance sheet as reasons to be optimistic (Simon Jessop)