Chelsea and Tottenham meet in the Premier League on Sunday when both clubs will be looking to put down a marker about their title aspirations.
Summer signings Timo Werner, Hakim Ziyech, Thiago Silva, Ben Chilwell, Edouard Mendy and Kai Havertz will all be getting their first taste of a London derby against Spurs.
Asked if they need to be told about the history of the rivalry, Hudson-Odoi said: “No, I think they know already. They know it is a big game. Every time Chelsea play Tottenham, everybody knows how big of a game it is.
“We want to win every game that we play against them. The new boys already know that it is going to be a massive game, it is going to be a tough one as well but we want to go out there and get the three points and hopefully we will be smiling at the weekend.
“It is a big derby, we want to beat them. It is a massive game. We are going to go in there confident. We have to make sure we recover well after Tuesday and hopefully get the three points.”
Hudson-Odoi hopes to be involved against Tottenham after scoring in Tuesday’s 2-1 Champions League win against Rennes.
“Every opportunity I get I want to take,” said the winger. “Every time I get an opportunity I want to impress as much as possible, get as many goals and assists as possible and work hard for the team as much as possible. Hopefully I can keep going and get more opportunities."