The game is taking place in Budapest, Hungary due to Germany’s coronavirus travel restrictions.
Gladbach have never got to this stage of the competition before and will be up against it when they take on the runaway Premier League leaders. The German club are currently eighth in the Bundesliga, outside the European places.
FOLLOW LIVE: Monchengladbach vs Man City – Latest updates
City are on an 18-game winning streak and the expectation is that they will keep that going tonight.
Here is everything you need to know.
When is the match?
Gladbach vs Man City kicks off tonight at 8pm GMT.
How can I watch it?
The game will be broadcast live on BT Sport in the UK. Subscribers can stream online via the BT Sport website and the BT Sport app.
What is the team news?
Pep Guardiola says every City player is now fit except for defender Nathan Ake. Marco Rose reports no injuries in his senior Gladbach squad.
Monchengladbach XI: Sommer, Elvedi, Zakaria, Ginter, Lainer, Neuhaus, Kramer, Hofmann, Bensebaini, Plea, Stindl
Man City XI: Ederson, Walker, Dias, Laporte, Cancelo, Gundogan, Rodri, Foden, Sterling, Jesus, Silva
Manchester City: WWWWWW
Manchester City 2/7
This Gladbach side are not in great form and manager Marco Rose’s announcement that he will depart for Dortmund in the summer cannot have helped matters. City are flying and should be far too good. Gladbach 0-3 City.