Dublin, June 16, 2021 (GLOBE NEWSWIRE) -- The "Market Spotlight: Gout" report has been added to ResearchAndMarkets.com's offering.
This Market Spotlight report covers the Gout market, comprising key marketed and pipeline drugs, clinical trials, upcoming events, recent events and analyst opinion, a 10-year disease prevalence forecast, probability of success, and licensing and acquisition deals, as well as presenting drug-specific revenue forecasts.
The publisher estimates that in 2019, there were 35.4 million prevalent cases of gout in people aged 15 years and older worldwide, and forecasts that number to increase to 39.4 million prevalent cases by 2028.
The approved drugs in the gout space focus on targets such as microtubules, URAT1, xanthine oxidase, interleukin-1, and uric acid. These drugs are commonly administered via the oral route, with the remainder being available in intravenous and subcutaneous formulations.
The largest proportion of industry-sponsored drugs in active clinical development for gout are in Phase I, with just a single product in Phase III.
Drugs in development for gout focus on targets such as uric acid, URAT1, xanthine oxidase, and NLR protein-3/inflammasome. The largest proportion of pipeline drugs are administered via the oral route, with the remainder being intravenous, intramuscular, and topical formulations.
High-impact upcoming events for drugs in the gout space comprise topline Phase II trial results for Krystexxa, and topline Phase III trial results for SEL-212.
The overall likelihood of approval of a Phase I arthritis asset is 9.6%, and the average probability a drug advances from Phase III is 80.8%. Drugs, on average, take 9.1 years from Phase I to approval in the arthritis space, as well as in the overall autoimmune/immunology space.
The distribution of clinical trials across Phase I-IV indicates that the majority of trials for gout have been in the early and midphases of development, with 71% of trials in Phase I-II, and 29% in Phase III-IV.
The US has a substantial lead in the number of gout clinical trials globally. Germany leads the major European markets, while Japan has the top spot in Asia.
Clinical trial activity in the gout space is dominated by completed trials. AstraZeneca has the highest number of completed clinical trials for gout, with 70 trials.
AstraZeneca leads industry sponsors with the highest overall number of clinical trials for gout.
Key Topics Covered:
Non-steroidal anti-inflammatory drugs (NSAIDs)
Prevention of chronic gout
RECENT EVENTS AND ANALYST OPINION
SEL-212 for Gout (September 30, 2020)
URC102 for Gout (September 27, 2019)
KEY UPCOMING EVENTS
PROBABILITY OF SUCCESS
LICENSING AND ASSET ACQUISITION DEALS
Sobi Pays $100m Upfront For Selecta Gout Drug
Eisai Acquires Chinese Rights To Fuji Hyperuricemia Drug
CLINICAL TRIAL LANDSCAPE
Sponsors by status
Sponsors by phase
For more information about this report visit https://www.researchandmarkets.com/r/mge0x2
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