With no fans allowed inside Anfield, Liverpool's players need all the confidence they can muster. Registering a first win — and first open-play goals — at home in 2021 could not have come at a better time in the Premier League victory over Aston Villa on Saturday.
With the soon-to-be-dethroned Premier League champions three points off the top-four pace, lifting the Champions League trophy in May could be their only ticket back into the competition next season.
A semi-final against Chelsea is up for grabs, and the prospect of an all-English last-four tie could just spur Liverpool on to another memorable European comeback.
Date, time and venue
Liverpool vs Real Madrid is scheduled for an 8pm BST kick-off tonight - Wednesday, April 14, 2021.
The match will be held behind closed doors at Anfield due to ongoing Covid-19 restrictions.
How to watch
TV channel: The match will be televised live on BT Sport 2 and BT Sport Ultimate, with coverage beginning at 7pm.
Live stream: BT Sport subscribers will be able to watch the match online via the website or BT Sport app.
Team news and lineups
Liverpool XI: Alisson; Alexander-Arnold, Phillips, Kabak, Robertson; Fabinho, Milner, Wijnaldum; Mane, Salah, Firmino
Subs: Adrian, H. Davies, Thiago, Keita, Oxlade-Chamberlain, Jota, Tsimikas, Shaqiri, B. Davies, Williams, Cain, Clarkson
Real Madrid XI: Courtois, Valverde, Eder Militao, Nacho, Mendy, Modric, Casemiro, Kroos, Asensio, Benzema, Vinicius Junior
Subs: Marcelo, Lunin, Odriozola, Isco, Mariano, Rodrygo, Altube, Park, Arribas, Chust
Referee: Bjorn Kuipers
Prediction: Liverpool 1-2 Real Madrid
Liverpool looked slightly back to their former selves against Aston Villa but still not a match for Real Madrid. An early goal will be key for them, but I can see the visitors killing the tie with an away goal.
Head to head (h2h) history and results
Liverpool wins: 3
Real Madrid wins: 4
Betting odds and tips (subject to change)
Liverpool to qualify: 7/2
Real Madrid to qualify: 1/4
Liverpool to qualify on penalties: 50/1
Odds via Betfair Exchange. Click here to find out more.