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Protein Inhibitors Global Market Report 2020-30: COVID-19 Growth and Change

·5-min read

Major players in the protein inhibitors market are Bayer AG, Astra Zeneca, Roche, Teva, Apotex, Novartis, GlaxoSmithKline, Pfizer, Boehringer Ingelheim and F. Hoffmann-La Roche. The global protein inhibitors market is expected to decline from $59.

New York, Dec. 18, 2020 (GLOBE NEWSWIRE) -- announces the release of the report "Protein Inhibitors Global Market Report 2020-30: COVID-19 Growth and Change" -
66 billion in 2019 to $56.97 billion in 2020 at a compound annual growth rate (CAGR) of -4.5%. The decline is mainly due to the COVID-19 outbreak that has led to restrictive containment measures involving social distancing, remote working, and the closure of industries and other commercial activities resulting in operational challenges. The entire supply chain has been disrupted, impacting the market negatively. The market is then expected to recover and reach $75.37 billion in 2023 at a CAGR of 9.78%.

The protein inhibitors market consists of sales of protein inhibitors by entities (organizations, sole traders, and partnerships) that are engaged in the manufacturing of protein inhibitors. Protein synthesis inhibitors stop the development of cells by disrupting the process leading to the generation of new proteins. Protein inhibitors is a pharmaceutical drug that acts on the proteins (special target) in the body and finds applications in the treatment of various diseases such as cancer, autoimmune diseases, infectious diseases, and others.

North America was the largest region in the protein inhibitors market. Asia Pacific is expected to have the fastest growth rate in the protein inhibitors market during the forecast period.

In December 2019, Sanofi S.A., a France-based pharmaceutical company, announced the acquisition of Synthorx, Inc., a biotechnology company, for $2.5 billion. The acquisition is aimed at boosting the immuno-oncology pipeline of Sanofi S.A. Synthorx Inc’s novel discovery platform has developed a molecule with the potential to become a foundation for the next generation of combination therapies for the treatment of cancer. THOR-707, by expanding the number of T-cells and natural killer cells in the body, can be combined with other oncology medicines for treating cancer. Synthorx, Inc. is a US-based company specializing in protein therapeutics for improving and prolonging the lives of people with autoimmune diseases, inflammatory diseases, and cancer.

The protein inhibitors market covered in this report is segmented by product into protein kinase inhibitors; monoclonal antibody; others, by application into oncology; inflammatory diseases; others, and by distribution channel into hospital pharmacies; independent pharmacies; online pharmacies.

The high cost of protein inhibitors used for cancer is anticipated to limit the growth of the protein inhibitors market in the near future. Monoclonal antibodies are a type of protein made in the laboratory to bind substances in the body including cancer cells and are used to treat various types of cancer. Monoclonal antibodies therapies are considered to be costlier when used for cancer. For instance, according to the National Center for Biotechnology Information, the average price of a monoclonal antibody was $96,731 for 34 monoclonal antibodies indication combinations. Oncology and hematology monoclonal antibodies represented 40% of approved monoclonal antibodies indication combinations, yet accounted for more than 85% of those priced $100,000 or higher. The price of oncology or hematology monoclonal antibodies was $149,622 higher than those used in metabolic or cardiovascular disorders, $106,830 higher than in ophthalmology, $128,856 higher than in infectious diseases or allergy, and $98,981 higher than in immunology. Thus, the high cost of protein inhibitors including monoclonal antibodies for the treatment of cancer is expected to hinder the market’s growth.

Companies in the protein inhibitors market are increasingly investing in various strategic initiatives such as partnerships and collaborations to develop new drugs to meet the market demand. Strategic collaborations and partnership agreements help companies to expand their existing product portfolio and geographical presence. For instance, in February 2020, Catalent Inc., a US-based provider of delivery technologies, drug manufacturing, gene therapies, biologics, and consumer healthcare products, announced the partnership agreement with Zumutor Biologics Inc., an immune-oncology company based in the USA, to manufacture ZM008, a monoclonal antibody targeting solid tumors. Moreover, in July 2018, Anima Biotech, a US-based biotechnology company announced a partnership agreement with Eli Lilly and Company, a US-based pharmaceutical company for the development and discovery of translation inhibitors of several protein targets using Anima Biotech’s translation control therapeutics platform.

The increasing prevalence of chronic diseases such as cancer, cardiovascular diseases, and autoimmune diseases is predicted to contribute to the growth of the protein inhibitors market. According to the World Health Organization, chronic diseases are expected to become the seventh leading cause of death globally, by the end of 2030. According to the National Health Council’s report published in 2019, there were approximately 133 million Americans affected by chronic diseases, estimated to be 40% of the total population of the country. The number is expected to reach 157 million by 2020, with 87 million people having multiple conditions. Protein inhibitors are used for the treatment of these diseases due to fewer adverse effects and higher efficacy. Therefore, the increasing number of people with chronic diseases is anticipated to drive the demand for the protein inhibitors market.
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