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Shire plc : Block listing Interim Review

BLOCK LISTING SIX MONTHLY RETURN

November 24, 2017 - Shire plc (LSE: SHP, NASDAQ: SHPG)

Name of applicant:

Shire plc

Name of scheme:

Shire Sharesave Scheme

Period of return:

From:

May 23, 2017

To:

November 22, 2017

Balance of unallotted securities under scheme(s) from previous return:

167,532

Plus: The amount by which the block scheme(s) has been increased since the date of the last return (if any increase has been applied for):

Nil

Less: Number of securities issued/allotted under scheme(s) during period (see LR3.5.7G):

4,012

Equals: Balance under scheme(s) not yet issued/allotted at end of period:

163,520

Name of applicant:

Shire plc

Name of scheme:

Shire Portfolio Share Plan

Period of return:

From:

May 23, 2017

To:

November 22, 2017

Balance of unallotted securities under scheme(s) from previous return:

360,742

Plus: The amount by which the block scheme(s) has been increased since the date of the last return (if any increase has been applied for):

Nil

Less: Number of securities issued/allotted under scheme(s) during period (see LR3.5.7G):

90,208

Equals: Balance under scheme(s) not yet issued/allotted at end of period:

270,534


Name of applicant:

Shire plc

Name of scheme:

Shire Employee Stock Purchase Plan

Period of return:

From:

May 23, 2017

To:

November 22, 2017

Balance of unallotted securities under scheme(s) from previous return:

237,698

Plus: The amount by which the block scheme(s) has been increased since the date of the last return (if any increase has been applied for):

Nil

Less: Number of securities issued/allotted under scheme(s) during period (see LR3.5.7G):

Nil

Equals: Balance under scheme(s) not yet issued/allotted at end of period:

237,698


Name of applicant:

Shire plc

Name of scheme:

Shire Long Term Incentive Plan 2015

Period of return:

From:

May 23, 2017

To:

November 22, 2017

Balance of unallotted securities under scheme(s) from previous return:

2,687,072

Plus: The amount by which the block scheme(s) has been increased since the date of the last return (if any increase has been applied for):

Nil

Less: Number of securities issued/allotted under scheme(s) during period (see LR3.5.7G):

188,501

Equals: Balance under scheme(s) not yet issued/allotted at end of period:

2,498,571


Name of applicant:

Shire plc

Name of scheme:

Shire Global Employee Stock Purchase Plan

Period of return:

From:

May 23, 2017

To:

November 22, 2017

Balance of unallotted securities under scheme(s) from previous return:

1,600,843

Plus: The amount by which the block scheme(s) has been increased since the date of the last return (if any increase has been applied for):

Nil

Less: Number of securities issued/allotted under scheme(s) during period (see LR3.5.7G):

800,060

Equals: Balance under scheme(s) not yet issued/allotted at end of period:

800,783


Name of applicant:

Shire plc

Name of scheme:

Baxalta Exchange Awards

Period of return:

From:

May 23, 2017

To:

November 22, 2017

Balance of unallotted securities under scheme(s) from previous return:

17,995,867

Plus: The amount by which the block scheme(s) has been increased since the date of the last return (if any increase has been applied for):

Nil

Less: Number of securities issued/allotted under scheme(s) during period (see LR3.5.7G):

765,528

Equals: Balance under scheme(s) not yet issued/allotted at end of period:

17,230,339


Name of applicant:

Shire plc

Name of scheme:

Combined block listing in respect of the Shire Portfolio Share Plan, the Shire Long Term Incentive Plan 2015 and the Shire Global Employee Stock Purchase Plan.

Period of return:

From:

July 7, 2017

To:

November 22, 2017

Balance of unallotted securities under scheme(s) from previous return:

N/A

Plus: The amount by which the block scheme(s) has been increased since the date of the last return (if any increase has been applied for):

3,000,000

Less: Number of securities issued/allotted under scheme(s) during period (see LR3.5.7G):

Shire Portfolio Share Plan: Nil

Shire Long Term Incentive Plan 2015: Nil

Shire Global Employee Stock Purchase Plan: Nil

Equals: Balance under scheme(s) not yet issued/allotted at end of period:

3,000,000



Amendment of Block listing six monthly return released May 23, 2017:

November 24, 2017 - Shire plc (LSE: SHP, NASDAQ: SHPG) announces that the Block listing six monthly return released May 23, 2017, has been amended to reflect the following:

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The number of securities issued/allotted under the Shire Portfolio Share Plan is amended from 405,083 to 408,873 and the balance not yet issued/allotted under this scheme is amended from 364,532 to 360,742.

The number of securities issued/allotted under the Shire Long Term Incentive Plan 2015 is amended from 145,740 to 149,340 and the balance not yet issued/allotted under this scheme is amended from 2,690,672 to 2,687,072.

The full amended announcement is below.

May 23, 2017 - Shire plc (LSE: SHP, NASDAQ: SHPG)

Name of applicant:

Shire plc

Name of scheme:

Shire Sharesave Scheme

Period of return:

From:

November 23, 2016

To:

May 22, 2017

Balance of unallotted securities under scheme(s) from previous return:

184,611

Plus: The amount by which the block scheme(s) has been increased since the date of the last return (if any increase has been applied for):

Nil

Less: Number of securities issued/allotted under scheme(s) during period (see LR3.5.7G):

17,079

Equals: Balance under scheme(s) not yet issued/allotted at end of period:

167,532

Name of applicant:

Shire plc

Name of scheme:

Shire Portfolio Share Plan

Period of return:

From:

November 23, 2016

To:

May 22, 2017

Balance of unallotted securities under scheme(s) from previous return:

769,615

Plus: The amount by which the block scheme(s) has been increased since the date of the last return (if any increase has been applied for):

Nil

Less: Number of securities issued/allotted under scheme(s) during period (see LR3.5.7G):

408,873

Equals: Balance under scheme(s) not yet issued/allotted at end of period:

360,742

Name of applicant:

Shire plc

Name of scheme:

Shire Employee Stock Purchase Plan

Period of return:

From:

November 23, 2016

To:

May 22, 2017

Balance of unallotted securities under scheme(s) from previous return:

244,057

Plus: The amount by which the block scheme(s) has been increased since the date of the last return (if any increase has been applied for):

Nil

Less: Number of securities issued/allotted under scheme(s) during period (see LR3.5.7G):

6,359

Equals: Balance under scheme(s) not yet issued/allotted at end of period:

237,698


Name of applicant:

Shire plc

Name of scheme:

Shire Long Term Incentive Plan 2015

Period of return:

From:

November 23, 2016

To:

May 22, 2017

Balance of unallotted securities under scheme(s) from previous return:

2,836,412

Plus: The amount by which the block scheme(s) has been increased since the date of the last return (if any increase has been applied for):

Nil

Less: Number of securities issued/allotted under scheme(s) during period (see LR3.5.7G):

149,340

Equals: Balance under scheme(s) not yet issued/allotted at end of period:

2,687,072


Name of applicant:

Shire plc

Name of scheme:

Shire Global Employee Stock Purchase Plan

Period of return:

From:

November 23, 2016

To:

May 22, 2017

Balance of unallotted securities under scheme(s) from previous return:

1,604,243

Plus: The amount by which the block scheme(s) has been increased since the date of the last return (if any increase has been applied for):

Nil

Less: Number of securities issued/allotted under scheme(s) during period (see LR3.5.7G):

3,400

Equals: Balance under scheme(s) not yet issued/allotted at end of period:

1,600,843


Name of applicant:

Shire plc

Name of scheme:

Baxalta Exchange Awards

Period of return:

From:

November 23, 2016

To:

May 22, 2017

Balance of unallotted securities under scheme(s) from previous return:

20,488,204

Plus: The amount by which the block scheme(s) has been increased since the date of the last return (if any increase has been applied for):

Nil

Less: Number of securities issued/allotted under scheme(s) during period (see LR3.5.7G):

2,492,337

Equals: Balance under scheme(s) not yet issued/allotted at end of period:

17,995,867


Name of contact:

Sarah Rixon, Company Secretarial Assistant

Telephone number of contact:

01256 894000

For further information please contact:

Investor Relations

Ian Karp

ikarp@shire.com

+1 781 482 9018

Robert Coates

rcoates@shire.com

+44 203 549 0874

Media

Lisa Adler

lisa.adler@shire.com

+1 617 588 8607

Katie Joyce

kjoyce@shire.com

+1 781 482 2779

NOTES TO EDITORS

About Shire

Shire is the global leader in serving patients with rare diseases. We strive to develop best-in-class therapies across a core of rare disease areas including hematology, immunology, genetic diseases, neuroscience, and internal medicine with growing therapeutic areas in ophthalmics and oncology. Our diversified capabilities enable us to reach patients in more than 100 countries who are struggling to live their lives to the fullest.

We feel a strong sense of urgency to address unmet medical needs and work tirelessly to improve people`s lives with medicines that have a meaningful impact on patients and all who support them on their journey.

www.shire.com




This announcement is distributed by Nasdaq Corporate Solutions on behalf of Nasdaq Corporate Solutions clients.

The issuer of this announcement warrants that they are solely responsible for the content, accuracy and originality of the information contained therein.
Source: Shire plc via GlobeNewswire

HUG#2151882