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Shire plc : Director/PDMR Shareholding

Director/PDMR Shareholding August 23, 2017 - Shire plc (LSE: SHP, NASDAQ: SHPG) Notification of transaction by person discharging managerial responsibilities

1.

Details of the person discharging managerial responsibilities ("PDMR") / person closely associated them ("PCA")

a)

Name

Sara Mathew

2.

Reason for the notification

a)

Position / status

Non-Executive Director (PDMR)

b)

Initial notification / amendment

Initial notification

3.

Details of the issuer, emission allowance participant, auction platform, auctioneer or auction monitor

a)

Name

Shire plc

b)

LEI

54930005LQRLI2UXRQ59

4.

Details of the transaction(s): section to be repeated for (i) each type of instrument; (ii) each type of transaction; (iii) each date; and (iv) each place where transactions have been conducted

a)

Description of the financial instrument, type of instrument

Shire plc American Depositary Shares ("ADSs")

Identification code

ISIN: US82481R1068

b)

Nature of the transaction

Acquisition of ADSs

c)

Price(s) and volume(s)

Price(s)

Volume(s)

$143.23

1,350

d)

Aggregated information

- Aggregated volume

- Price

N/A (single transaction)

e)

Date of the transaction

August 22, 2017

f)

Place of the transaction

NASDAQ Global Select Market

Sarah Rixon

Company Secretarial Assistant

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For further information please contact:

Investor Relations

Ian Karp

ikarp@shire.com

+1 781 482 9018

Robert Coates

rcoates@shire.com

+44 1256 894874

Media

Lisa Adler

lisa.adler@shire.com

+1 617 588 8607

Debbi Ford

debbi.ford@shire.com

+1 617 949 9083

NOTES TO EDITORS

About Shire

Shire is the leading global biotechnology company focused on serving people with rare diseases. We strive to develop best-in-class products, many of which are available in more than 100 countries, across core therapeutic areas including Hematology, Immunology, Neuroscience, Ophthalmics, Lysosomal Storage Disorders, Gastrointestinal / Internal Medicine / Endocrine and Hereditary Angioedema; and a growing franchise in Oncology.

Our employees come to work every day with a shared mission: to develop and deliver breakthrough therapies for the hundreds of millions of people in the world affected by rare diseases and other high-need conditions, and who lack effective therapies to live their lives to the fullest.

www.shire.com




This announcement is distributed by NASDAQ OMX Corporate Solutions on behalf of NASDAQ OMX Corporate Solutions clients.

The issuer of this announcement warrants that they are solely responsible for the content, accuracy and originality of the information contained therein.
Source: Shire plc via GlobeNewswire

HUG#2128728