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* FTSE 100 down 0.3%, FTSE 250 down 1.1%
* UK indexes ease after Friday's rally
* Sophos soars on buyout deal
Oct 14 (Reuters) - London-listed companies with exposure to the domestic economy retreated on Monday after last week's optimism around Brexit amid signs that more work was needed to sort out a deal, while cybersecurity firm Sophos soared 38% after a buyout offer.
The FTSE 100 gave up 0.3% by 0710 GMT. The FTSE 250 shed 1.2%, handing back part of the more than 4% gain it had recorded in the previous session, which was its best in more than nine years.
Britain and the European Union said over the weekend that a lot more work would be needed to secure a Brexit agreement.
Sophos Group surged to its highest in more than a year at 586.8 pence, after private equity firm Thoma Bravo said it would take the company private in a 583 pence per share deal. (Reporting by Shashwat Awasthi in Bengaluru; Editing by Bernard Orr)