Insider	Transaction	Type	Value	Date	Shares
Baillie Gifford International Choice Fund		Direct		30 Nov 2022	4,150,441
Bradshaw (John)	Exercise of Option at price 0.26 per share.	Direct	6,939	10 Aug 2022	27,000
Bradshaw (John)	Exercise of Option at price 0.93 per share.	Direct	73,341	10 Aug 2022	78,947
Gulliford (Craig Jonathan)		Direct		05 Aug 2022	246,194
Hancock (Christopher Paul)		Direct		05 Aug 2022	184,645
Rees (Richard)		Direct		05 Aug 2022	184,645
Hancock (Christopher Paul)	Bought at price 0.94 per share.	Direct	1,102	29 Jul 2022	1,177
Rees (Richard)	Bought at price 0.94 per share.	Direct	1,102	29 Jul 2022	1,177
Gulliford (Craig Jonathan)	Bought at price 0.94 per share.	Direct	1,102	29 Jul 2022	1,177
Axa Investment Managers UK Ltd		Direct		27 Jun 2022	0
Baillie Gifford International Choice Fund		Direct		27 Jun 2022	0
Capital Group		Direct		27 Jun 2022	0
Creo Medical Group Employee Benefit Trust		Direct		27 Jun 2022	0
Finance Wales Investments Ltd		Direct		27 Jun 2022	0
Gulliford (Craig Jonathan)		Direct		27 Jun 2022	0
Hancock (Christopher Paul)		Direct		27 Jun 2022	0
Hargreave Hale Ltd		Direct		27 Jun 2022	0
M&G Alternatives Investment Management, Ltd.		Direct		27 Jun 2022	0
Rees (Richard)		Direct		27 Jun 2022	0
Woods (David)		Direct		27 Jun 2022	0
Tellworth Investments LLP		Direct		27 Jun 2022	0
Spicer (Charles Alexander Evan)		Direct		27 Jun 2022	0
Spicer (Charles Alexander Evan)	Bought at price 1.22 per share.	Direct	18,861	26 May 2022	15,435
Rees (Richard)	Bought at price 1.22 per share.	Direct	85,540	26 May 2022	70,000
Hargreave Hale Ltd		Direct		16 May 2022	1,839,769
Hancock (Christopher Paul)		Direct		31 Dec 2021	0
Hargreave Hale Ltd		Direct		31 Dec 2021	0
Rees (Richard)		Direct		31 Dec 2021	0
Axa Investment Managers UK Ltd		Direct		31 Dec 2021	0
Baillie Gifford International Choice Fund		Direct		31 Dec 2021	0
Capital Group		Direct		31 Dec 2021	0
Creo Medical Group Employee Benefit Trust		Direct		31 Dec 2021	0
Finance Wales Investments Ltd		Direct		31 Dec 2021	0
Gulliford (Craig Jonathan)		Direct		31 Dec 2021	0
Tellworth Investments LLP		Direct		31 Dec 2021	0
Woods (David)		Direct		31 Dec 2021	0
Spicer (Charles Alexander Evan)		Direct		31 Dec 2021	0
Spicer (Charles Alexander Evan)	Bought at price 2.52 per share.	Direct	24,354	07 Sept 2021	9,657
Hargreave Hale Ltd		Direct		07 Sept 2021	1,175,557
Capital Group		Direct		03 Sept 2021	6,092,656
Gulliford (Craig Jonathan)	Bought at price 0.83 per share.	Direct	1,243	26 Jul 2021	1,500
Rees (Richard)	Bought at price 0.83 per share.	Direct	1,243	26 Jul 2021	1,500
Hargreave Hale Ltd		Direct		17 Feb 2021	1,542,700
Hancock (Christopher Paul)		Direct		31 Dec 2020	0
Hancock (Christopher Paul)		Direct		31 Dec 2020	0
Hargreave Hale Ltd		Direct		31 Dec 2020	0
Hargreave Hale Ltd		Direct		31 Dec 2020	0
Hoya Corporation		Direct		31 Dec 2020	0
Hoya Corporation		Direct		31 Dec 2020	0
M&G Alternatives Investment Management, Ltd.		Direct		31 Dec 2020	0
M&G Alternatives Investment Management, Ltd.		Direct		31 Dec 2020	0
Spicer (Charles Alexander Evan)		Direct		31 Dec 2020	0
Spicer (Charles Alexander Evan)		Direct		31 Dec 2020	0
Tellworth Investments LLP		Direct		31 Dec 2020	0
Woods (David)		Direct		31 Dec 2020	0
Woods (David)		Direct		31 Dec 2020	0
Tellworth Investments LLP		Direct		31 Dec 2020	0
Axa Investment Managers UK Ltd		Direct		31 Dec 2020	0
Axa Investment Managers UK Ltd		Direct		31 Dec 2020	0
Baillie Gifford International Choice Fund		Direct		31 Dec 2020	0
Baillie Gifford International Choice Fund		Direct		31 Dec 2020	0
Capital Group		Direct		31 Dec 2020	0
Capital Group		Direct		31 Dec 2020	0
Creo Medical Group Employee Benefit Trust		Direct		31 Dec 2020	0
Creo Medical Group Employee Benefit Trust		Direct		31 Dec 2020	0
Fidelity International		Direct		31 Dec 2020	0
Fidelity International		Direct		31 Dec 2020	0
Finance Wales Investments Ltd		Direct		31 Dec 2020	0
Finance Wales Investments Ltd		Direct		31 Dec 2020	0
Gulliford (Craig Jonathan)		Direct		31 Dec 2020	0
Gulliford (Craig Jonathan)		Direct		31 Dec 2020	0
Hargreave Hale Ltd		Direct		25 Aug 2020	808,396
Spicer (Charles Alexander Evan)	Bought at price 2.61 per share.	Direct	63,943	24 Jul 2020	24,509
Hargreave Hale Ltd		Direct		21 Feb 2020	525,771
Hancock (Christopher Paul)		Direct		31 Dec 2019	0
Hargreave Hale Ltd		Direct		31 Dec 2019	0
Hoya Corporation		Direct		31 Dec 2019	0
M&G Alternatives Investment Management, Ltd.		Direct		31 Dec 2019	0
Spicer (Charles Alexander Evan)		Direct		31 Dec 2019	0
Axa Investment Managers UK Ltd		Direct		31 Dec 2019	0
Baillie Gifford International Choice Fund		Direct		31 Dec 2019	0
Fidelity International		Direct		31 Dec 2019	0
Finance Wales Investments Ltd		Direct		31 Dec 2019	0
Gulliford (Craig Jonathan)		Direct		31 Dec 2019	0
Woods (David)		Direct		31 Dec 2019	0
Tellworth Investments LLP		Direct		31 Dec 2019	0
Woods (David)	Bought at price 2.33 per share.	Direct	58,250	24 Dec 2019	25,000
M&G Alternatives Investment Management, Ltd.		Direct		24 Dec 2019	0
Spicer (Charles Alexander Evan)	Bought at price 2.33 per share.	Direct	32,154	24 Dec 2019	13,800
Spicer (Charles Alexander Evan)	Bought at price 1.71 per share.	Direct	24,387	06 Aug 2019	14,220
Hargreave Hale Ltd		Direct		05 Apr 2019	92,660
Hargreave Hale Ltd		Direct		13 Mar 2019	613,225
Hancock (Christopher Paul)		Direct		31 Dec 2018	0
Hargreave Hale Ltd		Direct		31 Dec 2018	0
Hoya Corporation		Direct		31 Dec 2018	0
Legal & General Group Plc		Direct		31 Dec 2018	0
Spicer (Charles Alexander Evan)		Direct		31 Dec 2018	0
Tellworth Investments LLP		Direct		31 Dec 2018	0
Baillie Gifford International Choice Fund		Direct		31 Dec 2018	0
Fidelity International		Direct		31 Dec 2018	0
Finance Wales Investments Ltd		Direct		31 Dec 2018	0
Gulliford (Craig Jonathan)		Direct		31 Dec 2018	0
Morris (Steven)	Exercise of Option at price 0.21 per share.	Direct	69,216	22 Nov 2018	336,000
Hargreave Hale Ltd		Direct		19 Oct 2018	115,847
Hargreave Hale Ltd		Direct		10 Oct 2018	79,511
Hargreave Hale Ltd		Direct		01 Oct 2018	8,598,216
Hancock (Christopher Paul)	Sold at price 1.63 per share.	Direct	780,480	30 Aug 2018	480,000
Hargreave Hale Ltd		Direct		30 Aug 2018	7,092,756
Baillie Gifford International Choice Fund		Direct		30 Aug 2018	0
Gulliford (Craig Jonathan)	Sold at price 1.63 per share.	Direct	780,480	30 Aug 2018	480,000
Gulliford (Craig Jonathan)		Direct		15 Aug 2018	0
Hancock (Christopher Paul)		Direct		15 Aug 2018	0
Hargreave Hale Ltd	Bought at price 1.63 per share.	Direct	13,285,268	02 Aug 2018	8,165,500
Hargreave Hale Ltd		Direct		17 Jul 2018	72,744
Hargreave Hale Ltd		Direct		12 Jul 2018	89,001
Morris (Steven)	Sold at price 0.92 per share.	Direct	105,915	09 Jan 2018	115,000
Morris (Steven)	Bought at price 0.92 per share.	Direct	106,214	09 Jan 2018	115,325
Morris (Steven)	Exercise of Option at price 0.22 per share.	Direct	24,840	03 Jan 2018	115,000
Hancock (Christopher Paul)	Sold at price 0.94 per share.	Direct	34,402	21 Dec 2017	36,716
Hancock (Christopher Paul)	Bought at price 0.94 per share.	Direct	34,354	21 Dec 2017	36,664
Hargreave Hale Ltd		Direct		18 Sept 2017	0
Hargreave Hale Ltd		Direct		14 Sept 2017	53,551
Hargreave Hale Ltd		Direct		30 Aug 2017	171,700
Hargreave Hale Ltd		Direct		30 Jun 2017	0
Hoya Corporation		Direct		30 Jun 2017	0
Legal & General Group Plc		Direct		30 Jun 2017	0
RBC Trustees (CI),Ltd.		Direct		30 Jun 2017	0
Spicer (Charles Alexander Evan)		Direct		30 Jun 2017	0
Angel CoFund		Direct		30 Jun 2017	0
Cotterford Co., Ltd.		Direct		30 Jun 2017	0
Craton (Jonathan)		Direct		30 Jun 2017	0
Farmer (Mark)		Direct		30 Jun 2017	0
Finance Wales Investments Ltd		Direct		30 Jun 2017	0
Gulliford (Craig Jonathan)		Direct		30 Jun 2017	0
Hancock (Christopher Paul)		Direct		30 Jun 2017	0
Gulliford (Craig Jonathan)	Sold at price 1.03 per share.	Direct	95,718	04 Apr 2017	92,750
Gulliford (Craig Jonathan)	Bought at price 1.03 per share.	Direct	95,670	04 Apr 2017	92,704
Hancock (Christopher Paul)	Sold at price 1.03 per share.	Direct	109,478	04 Apr 2017	106,084
Hancock (Christopher Paul)	Bought at price 1.03 per share.	Direct	109,478	04 Apr 2017	106,084
Gulliford (Craig Jonathan)	Sold at price 1.19 per share.	Direct	120,203	01 Feb 2017	101,096
Gulliford (Craig Jonathan)	Bought at price 1.19 per share.	Direct	127,142	01 Feb 2017	106,932
Angel CoFund		Direct		09 Dec 2016	0
Cotterford Co., Ltd.		Direct		09 Dec 2016	0
Craton (Jonathan)		Direct		09 Dec 2016	0
Farmer (Mark)		Direct		09 Dec 2016	0
Finance Wales Investments Ltd		Direct		09 Dec 2016	0
Gulliford (Craig Jonathan)		Direct		09 Dec 2016	0
Hancock (Christopher Paul)		Direct		09 Dec 2016	0
Hargreave Hale Ltd		Direct		09 Dec 2016	0
Hoya Corporation		Direct		09 Dec 2016	0

FTSE 1008,237.72-34.74(-0.42%)

FTSE 25020,442.35-56.37(-0.27%)

AIM772.57+0.19(+0.02%)

GBP/EUR1.1822+0.0000(+0.00%)

GBP/USD1.2650-0.0010(-0.08%)

Bitcoin GBP50,927.66+135.29(+0.27%)

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Creo Medical Limited (CREO.L)

Insider transactions

Insider transactions reported - last two years

FTSE 100
8,237.72
-34.74(-0.42%)

FTSE 250
20,442.35
-56.37(-0.27%)

AIM
772.57
+0.19(+0.02%)

GBP/EUR
1.1822
+0.0000(+0.00%)

GBP/USD
1.2650
-0.0010(-0.08%)

Bitcoin GBP
50,927.66
+135.29(+0.27%)