|Bid||7.50 x 0|
|Ask||8.25 x 0|
|Day's range||7.51 - 8.50|
|52-week range||0.95 - 19.00|
|Beta (5Y monthly)||0.20|
|PE ratio (TTM)||N/A|
|Forward dividend & yield||N/A (N/A)|
|1y target est||N/A|
LONDON, March 01, 2021 (GLOBE NEWSWIRE) -- OKYO Pharma Limited ("OKYO" or the "Company") today announces that it has issued 250,000 ordinary shares of no par value ("Ordinary Shares"), credited as fully paid, at a price of 4.5p per share on the exercise of 250,000 options. Applications will be made to the FCA and to the London Stock Exchange for Admission in respect of all the 250,000 Ordinary Shares. It is expected that Admission will become effective, and that dealings in the new Ordinary Shares are expected to commence, at 8.00 a.m. on 3 March 2021. Following Admission of the new Ordinary Shares, the enlarged Share Capital will be 672,816,302 ordinary shares of no par value. The person who arranged for the release of this announcement on behalf of the Company was Keeren Shah, Chief Financial Officer of OKYO. THIS ANNOUNCEMENT CONTAINS INSIDE INFORMATION FOR THE PURPOSES OF UK MARKET ABUSE REGULATION. About OKYO OKYO Pharma Limited (LSE: OKYO) is a life sciences and biotechnology company admitted to listing on the standard segment of the Official List of the UK Financial Conduct Authority and to trading on the Main Market for listed securities of the London Stock Exchange plc. OKYO is focusing on the discovery and development of novel molecules to treat inflammatory dry eye diseases and ocular pain. Enquiries: OKYO Pharma LimitedWilly Simon+44 (0)20 7495 2379Optiva Securities LimitedRobert Emmet+44 (0)20 3981 4173 For further information, please visit the Company's website at www.okyopharma.com.
LONDON, Feb. 23, 2021 (GLOBE NEWSWIRE) -- OKYO Pharma Limited ("OKYO" or the "Company"), a biotechnology company focused on the development of novel drugs to treat inflammatory eye diseases and chronic ocular pain, today announced that patent No. 10,899,796 entitled “Compounds and Methods for Treating Pain” was issued by the United States Patent and Trademark Office (“USPTO”) on January 26, 2021. This patent covers a class of bovine adrenal medulla (BAM) peptides linked to specific lipids that demonstrate potential for treating symptoms of neuropathic pain, ocular pain, ocular inflammation and/or dry eye disease. The work recited in this patent lays out the potential of this class of lipidated BAM analogues as non-opioid analgesics for ocular pain management without the side effects and potential abuse associated with opioid medications. The Company originally announced in February 2018 that it had obtained exclusive licenses from On Target Therapeutics LLC and Tufts Medical Center, respectively, covering this ophthalmic disease drug program. These licenses included the rights to the intellectual property (IP) estate covering composition-of-matter and methodology claims on these lipid-linked analogues. “The publication of this patent on our BAM-lipidated analogues provides key IP protection crucial for bringing forward a candidate from this class into the clinic,” said Dr. Gary S. Jacob, CEO of OKYO. “It is important to recognize that the novel element of these drug candidates is the lipid anchor component of the molecule which we believe is the ‘secret sauce’ in seeing a pharmacologic benefit in the environment of the eye where tearing and other physiologic phenomena normally work against the effectiveness of drugs due to washout. We will be working hard to bring our lead BAM candidate forward for filing an IND as we move through 2021.” About OKYO Pharma OKYO Pharma Limited (LSE: OKYO) is a life sciences and biotechnology company admitted to listing on the standard segment of the Official List of the UK Financial Conduct Authority and to trading on the Main Market for listed securities of the London Stock Exchange plc. OKYO is focusing on the discovery and development of novel molecules to treat inflammatory dry eye diseases and chronic pain. Enquiries: OKYO Pharma LimitedWilly Simon+44 (0)20 7495 2379Optiva Securities LimitedRobert Emmet+44 (0)20 3981 4173 For further information, please visit the Company's website at www.okyopharma.com.
LONDON and BOSTON, Jan. 19, 2021 (GLOBE NEWSWIRE) -- OKYO (LSE: OKYO; OTCQB: EMMLF), the life sciences and biotechnology company focused on the discovery and development of novel molecules to treat inflammatory dry eye diseases and chronic pain, announces that it has today submitted a patent application for the potential use of chemerin and chemerin analogues for prophylaxis against and treatment of symptoms associated with, or resulting from, infection with SARS-CoV-2 virus, including inflammation due to the cytokine storm caused by COVID-19 disease (“COVID-19”), and acute respiratory distress syndrome (“ARDS”). OKYO has been developing the chemerin molecule as a promising anti-inflammatory treatment for dry-eye disease (“DED”) licensed from researchers at On Target Therapeutics LLC. OKYO has previously announced that it anticipates making an investigational new drug submission with the US Food and Drug Administration for the use of chemerin in the treatment of DED. “Together with On Target Therapeutics LLC, we have been exploring chemerin and associated analogues for other potential therapeutic uses and are now also focusing on chemerin as a novel approach to treating COVID-19 and ARDS patients,” said Dr. Gary S. Jacob, CEO of OKYO. “We are working aggressively to expand this COVID-19 work and will be providing progress on this project as important developments occur.” Dr. Napoleone Ferrara, a member of OKYO’s Scientific Advisory Board, will be spearheading this effort at OKYO to advance chemerin and its associated analogues for the treatment of patients with SARS-CoV-2 virus and ARDS. Dr. Ferrara, winner of the prestigious Lasker award and a member of the National Academy of Sciences USA, was the scientist who isolated vascular endothelial growth factor (VEGF), a discovery that led to the two blockbuster drugs Lucentis® and Avastin® (which together accounted for over US$9 billion in sales in 2019) as well as to the class of anti-VEGF drugs, which are widely used to treat cancer and intraocular neovascular diseases. Dr. Ferrara commented: "We are very excited to be working with our collaborating industry and academic partners to develop this promising addition to the COVID-19 therapeutic armamentarium and, of course, to expedite evaluation in patients as soon as possible. Beyond COVID-19, chemerin, which is a well-established modulator of inflammation, has promise for treating ARDS, a pathological condition that may be triggered by a host of insults to the lungs (e.g., pneumonia, sepsis, pancreatitis and inhalation injury).” About Chemerin and its receptor: The chemerin receptor (“CMKLR1”, also known as ChemR23) is a chemokine like G protein-coupled receptor (“GPCR”) expressed on select populations of cells, including inflammatory mediators (including macrophages, monocytes, plasmacytoid/myeloid dendritic cells and natural killer cells), as well as epithelial cells. Activation of CMKLR1 by its endogenous peptide ligand chemerin is known to modulate inflammation, but natural ligands for CMKLR1 have short half-lives due to rapid inactivation. Discovery of a stable, high potency CMKLR1 agonist (stable lipidated chemerin) by On Target Therapeutics LLC provided an important step toward the development of a new class of anti-inflammatory therapeutics. The person who arranged for the release of this announcement on behalf of the Company was Dr. Gary S. Jacob, Chief Executive Officer of OKYO. Notes for Editors: About OKYO OKYO Pharma Limited (LSE: OKYO; OTCQB: EMMLF) is a life sciences and biotechnology company admitted to listing on the standard segment of the Official List of the UK Financial Conduct Authority and to trading on the main market for listed securities of London Stock Exchange plc. OKYO is focusing on the discovery and development of novel molecules to treat inflammatory dry eye diseases and chronic pain. About Dr. Napoleone Ferrara Dr. Ferrara is a member of The National Academy of Sciences and has received numerous prestigious awards, including the Lasker Award and the Breakthrough Prize in Life Sciences. His research on understanding the role of angiogenesis and vascular endothelial growth factor (VEGF) in cancer development, led to the discovery that VEGF is a key mediator of angiogenesis associated with intraocular neovascular syndromes. This pioneering research led to the clinical development of a humanized anti-VEGF Fab (Ranibizumab, Lucentis®), which has also been approved as a therapy for neovascular age-related macular degeneration (AMD), retinal vein occlusion and diabetic macular edema. Ranibizumab and other anti-VEGF agents have had a dramatic impact on the development of therapies for these blinding disorders. When Lucentis® (Ranibizumab) received FDA approval in late June 2006, the new macular degeneration drug was celebrated as a major medical breakthrough. Dr. Ferrara's research also led to the development and approval of humanized anti-VEGF mAbs (Bevacizumab; Avastin®) for cancer treatment, with Avastin® being one of the bestselling cancer drugs over the last two decades. Lucentis® and Avastin® collectively achieved over $9 billion in sales in 2019. Forward-Looking Statements: Certain statements made in this announcement are forward-looking statements. These forward-looking statements are not historical facts but rather are based on the Company's current expectations, estimates, and projections about its industry; its beliefs; and assumptions. Words such as 'anticipates,' 'expects,' 'intends,' 'plans,' 'believes,' 'seeks,' 'estimates,' and similar expressions are intended to identify forward-looking statements. These statements are not guarantees of future performance and are subject to known and unknown risks, uncertainties, and other factors, some of which are beyond the Company's control, are difficult to predict, and could cause actual results to differ materially from those expressed or forecasted in the forward-looking statements. The Company cautions security holders and prospective security holders not to place undue reliance on these forward-looking statements, which reflect the view of the Company only as of the date of this announcement. The forward-looking statements made in this announcement relate only to events as of the date on which the statements are made. The Company will not undertake any obligation to release publicly any revisions or updates to these forward-looking statements to reflect events, circumstances, or unanticipated events occurring after the date of this announcement except as required by law or by any appropriate regulatory authority. For further information, please visit the Company's website at www.okyopharma.com. NOT FOR RELEASE, PUBLICATION OR DISTRIBUTION, IN WHOLE OR IN PART, IN OR INTO OR FROM ANY JURISDICTION WHERE TO DO SO WOULD CONSTITUTE A VIOLATION OF THE RELEVANT LAWS OF SUCH JURISDICTION THIS ANNOUNCEMENT CONTAINS INSIDE INFORMATION FOR THE PURPOSES OF ARTICLE 7 OF REGULATION (EU) NO 596/2014 Enquiries: OKYO Pharma LimitedGary S. Jacob, Chief Executive OfficerGabriele Cerrone, Non-Executive Chairman+44 (0)20 7495 2379 Optiva Securities Limited (Broker)Robert Emmet+44 (0)20 3981 4173 RedChip Companies Inc. (Investor Relations)Dave Gentrydave@redchip.com+1 407-491-4498