Insider	Transaction	Type	Value	Date	Shares
Hill (Adam)	Bought at price 0.70 per share.	Direct	5,587	21 Sept 2022	8,005
UBS Limited		Direct		04 Aug 2022	0
UBS Limited		Direct		16 Jun 2022	0
UBS Limited		Direct		03 Jun 2022	0
UBS Limited		Direct		27 May 2022	0
UBS Limited		Direct		19 May 2022	0
UBS Limited		Direct		16 May 2022	0
UBS Limited		Direct		29 Apr 2022	0
Hall (Matthew)	Exercise of Option at price 1.46 per share.	Direct	114,852	13 Apr 2022	78,882
Hall (Matthew)	Sold at price 1.65 per share.	Direct	130,313	13 Apr 2022	78,882
UBS Limited		Direct		31 Mar 2022	0
Hall (Matthew)	Exercise of Option at price 1.44 per share.	Direct	14,370	25 Mar 2022	10,000
Hall (Matthew)	Sold at price 1.78 per share.	Direct	17,800	25 Mar 2022	10,000
Hall (Matthew)	Exercise of Option at price 1.44 per share.	Direct	28,740	24 Mar 2022	20,000
Hall (Matthew)	Sold at price 1.85 per share.	Direct	36,920	24 Mar 2022	20,000
Schmidt (Meinhard)	Bought at price 0.01 per share.	Direct	2,941	18 Mar 2022	226,250
UBS Limited		Direct		07 Mar 2022	41,885
Hill (Adam)	Bought at price 1.74 per share.	Direct	13,130	07 Mar 2022	7,533
UBS Limited		Direct		17 Feb 2022	0
Hill (Adam)	Bought at price 2.25 per share.	Direct	12,766	23 Dec 2021	5,669
Hill (Adam)	Bought at price 2.21 per share.	Direct	13,263	21 Dec 2021	5,988
Balderton Capital III, L. P.		Direct		30 Sept 2021	0
Bunting (Timothy Brian)		Direct		30 Sept 2021	0
Chelverton Asset Management Ltd		Direct		30 Sept 2021	0
Credit Suisse Securities (Europe)		Direct		30 Sept 2021	0
Genostics Company, Ltd.		Direct		30 Sept 2021	0
Hargreaves Lansdown Asset Management Ltd.		Direct		30 Sept 2021	0
Hill (Adam)		Direct		30 Sept 2021	0
Schmidt (Meinhard)		Direct		30 Sept 2021	0
Sharp (Richard Simon)		Direct		30 Sept 2021	0
UBS Securities LLC		Direct		30 Sept 2021	0
Schmidt (Meinhard)		Direct		31 May 2021	0
Schroeder (Carsten)		Direct		31 May 2021	0
Sharp (Richard Simon)		Direct		31 May 2021	0
Balderton Capital III, L. P.		Direct		31 May 2021	0
Barclays, PLC		Direct		31 May 2021	0
Bunting (Timothy Brian)		Direct		31 May 2021	0
Chelverton Asset Management Ltd		Direct		31 May 2021	0
Credit Suisse Securities (Europe)		Direct		31 May 2021	0
Genostics Company, Ltd.		Direct		31 May 2021	0
Hamilton-Fairley (Geoffrey Neil)		Direct		31 May 2021	0
Hargreaves Lansdown Asset Management Ltd.		Direct		31 May 2021	0
Hill (Adam)		Direct		31 May 2021	0
Chelverton Asset Management Ltd		Direct		01 Apr 2021	0
Balderton Capital III, L. P.		Direct		30 Mar 2021	0
Genostics Company, Ltd.		Direct		30 Mar 2021	2,948,486
Genostics Company, Ltd.	Sold at price 2.50 per share.	Direct	100,000	11 Jan 2021	40,000
Genostics Company, Ltd.	Sold at price 2.51 per share.	Direct	25,090	08 Jan 2021	10,000
Genostics Company, Ltd.	Sold at price 2.32 per share.	Direct	115,799	05 Jan 2021	50,000
Genostics Company, Ltd.	Sold at price 2.38 per share.	Direct	119,200	05 Jan 2021	50,000
Genostics Company, Ltd.	Sold at price 2.29 per share.	Direct	11,445	21 Dec 2020	5,000
Hill (Adam)	Bought at price 2.35 per share.	Direct	13,545	17 Dec 2020	5,764
Genostics Company, Ltd.	Sold at price 2.24 per share.	Direct	67,140	14 Dec 2020	30,000
Genostics Company, Ltd.	Sold at price 2.18 per share.	Direct	21,820	11 Dec 2020	10,000
Hill (Adam)		Direct		10 Sept 2020	0
Hall (Matthew)		Direct		05 Jun 2020	0
Hill (Adam)		Direct		05 Jun 2020	0
Bunting (Timothy Brian)	Bought at price 1.51 per share.	Direct	90,660	04 Jun 2020	60,000
Bunting (Timothy Brian)	Bought at price 1.50 per share.	Direct	134,910	04 Jun 2020	90,000
Hall (Matthew)	Bought at price 1.49 per share.	Direct	1,890	04 Jun 2020	1,272
Hill (Adam)	Bought at price 1.49 per share.	Direct	12,602	04 Jun 2020	8,481
Kirschner (Ron)	Bought at price 1.51 per share.	Direct	2,496	04 Jun 2020	1,652
Schmidt (Meinhard)	Bought at price 1.47 per share.	Direct	11,783	04 Jun 2020	8,000
Schmidt (Meinhard)	Bought at price 1.52 per share.	Direct	7,620	04 Jun 2020	5,000
Sharp (Richard Simon)		Direct		04 Jun 2020	166,251
Ruffer LLP		Direct		31 May 2020	0
Schmidt (Meinhard)		Direct		31 May 2020	0
Schroeder (Carsten)		Direct		31 May 2020	0
Sharp (Richard Simon)		Direct		31 May 2020	0
Sharp (Richard Simon)		Direct		31 May 2020	0
Balderton Capital III, L. P.		Direct		31 May 2020	0
Bunting (Timothy Brian)		Direct		31 May 2020	0
Bunting (Timothy Brian)		Direct		31 May 2020	0
Credit Suisse Securities (Europe)		Direct		31 May 2020	0
Genostics Company, Ltd.		Direct		31 May 2020	0
Hamilton-Fairley (Geoffrey Neil)		Direct		31 May 2020	0
Hill (Adam)		Direct		31 May 2020	0
Premier Asset Management		Direct		31 May 2020	0
University of Nottingham		Direct		29 May 2020	1,650,000
Schroeder (Carsten)	Bought at price 1.06 per share.	Direct	19,044	04 May 2020	18,000
Ruffer LLP		Direct		29 Apr 2020	334,239
Hall (Matthew)	Bought at price 1.05 per share.	Direct	1,235	24 Apr 2020	1,176
Hill (Adam)	Bought at price 1.11 per share.	Direct	12,366	24 Apr 2020	11,111
Hall (Matthew)	Bought at price 0.65 per share.	Direct	6,204	07 Apr 2020	9,487
Hill (Adam)	Bought at price 0.58 per share.	Direct	12,408	01 Apr 2020	21,321
Schmidt (Meinhard)	Bought at price 0.58 per share.	Direct	10,368	24 Mar 2020	18,000
Hamilton-Fairley (Geoffrey Neil)	Bought at price 0.48 per share.	Direct	11,900	18 Mar 2020	25,000
Hamilton-Fairley (Geoffrey Neil)	Sold at price 0.90 per share.	Direct	22,575	10 Mar 2020	25,000
Schroeder (Carsten)	Bought at price 0.69 per share.	Direct	6,227	28 Feb 2020	9,000
Ruffer LLP		Direct		31 Oct 2019	0
Sharp (Richard Simon)		Direct		31 Oct 2019	0
University of Nottingham		Direct		31 Oct 2019	0
Balderton Capital III, L. P.		Direct		31 Oct 2019	0
Bunting (Timothy Brian)		Direct		31 Oct 2019	0
FIL Investments International		Direct		31 Oct 2019	0
Genostics Company, Ltd.		Direct		31 Oct 2019	0
Hamilton-Fairley (Geoffrey Neil)		Direct		31 Oct 2019	0
Balderton Capital III, L. P.		Direct		31 May 2019	0
Bunting (Timothy Brian)		Direct		31 May 2019	0
FIL Investments International		Direct		31 May 2019	0
Genostics Company, Ltd.		Direct		31 May 2019	0
Hamilton-Fairley (Geoffrey Neil)		Direct		31 May 2019	0
Ruffer LLP		Direct		31 May 2019	0
Sharp (Richard Simon)		Direct		31 May 2019	0
University of Nottingham		Direct		31 May 2019	0
Robertson (John Forsyth Russell)		Direct		10 Apr 2019	796,383
Aviva Investors Global Services Limited		Direct		29 Mar 2019	1,015,727
Qiagen Nv	Bought at price 2.06 per share.	Direct	1,776,088	25 Mar 2019	862,179
Balderton Capital III, L. P.		Direct		31 May 2018	0
Black (Andrew)		Direct		31 May 2018	0
Bunting (Timothy Brian)		Direct		31 May 2018	0
Genostics Company, Ltd.		Direct		31 May 2018	0
Hamilton-Fairley (Geoffrey Neil)		Direct		31 May 2018	0
Millet (Andrew)		Direct		31 May 2018	0
Robertson (John Forsyth Russell)		Direct		31 May 2018	0
Ruffer LLP		Direct		31 May 2018	0
Sharp (Richard Simon)		Direct		31 May 2018	0
University of Nottingham		Direct		31 May 2018	0
Robertson (John Forsyth Russell)		Direct		02 Feb 2018	1,023,096
University of Nottingham		Direct		02 Feb 2018	4,317,287
Genostics Company, Ltd.	Bought at price 2.20 per share.	Direct	9,885,255	02 Feb 2018	4,487,179
Aviva Investors Global Services Limited		Direct		28 Nov 2017	81,373
Ruffer LLP		Direct		03 Oct 2017	0
Royds (David J G)		Direct		06 Jul 2017	563,980
Robertson (John Forsyth Russell)		Direct		31 May 2017	0
Royds (David J G)		Direct		31 May 2017	0
Scott (Andrew)		Direct		31 May 2017	0
Sharp (Richard Simon)		Direct		31 May 2017	0
University of Nottingham		Direct		31 May 2017	0
Aviva Investors Global Services Limited		Direct		31 May 2017	0
Balderton Capital III, L. P.		Direct		31 May 2017	0
Black (Andrew)		Direct		31 May 2017	0
Bunting (Timothy Brian)		Direct		31 May 2017	0
Hamilton-Fairley (Geoffrey Neil)		Direct		31 May 2017	0
Millet (Andrew)		Direct		31 May 2017	0
Robertson (John Forsyth Russell)		Direct		24 Mar 2017	448,167
Robertson (John Forsyth Russell)		Direct		27 Oct 2016	0
Royds (David J G)		Direct		27 Oct 2016	0
Scott (Andrew)		Direct		27 Oct 2016	0
Sharp (Richard Simon)		Direct		27 Oct 2016	0
University of Nottingham		Direct		27 Oct 2016	0
Aviva Investors Global Services Limited		Direct		27 Oct 2016	0
Balderton Capital III, L. P.		Direct		27 Oct 2016	0
Black (Andrew)		Direct		27 Oct 2016	0
Bunting (Timothy Brian)		Direct		27 Oct 2016	0
Hamilton-Fairley (Geoffrey Neil)		Direct		27 Oct 2016	0
Oncimmune Employee Benefit Trust		Direct		27 Oct 2016	0
Millet (Andrew)		Direct		31 May 2016	0
Aviva Investors Global Services Limited		Direct		18 May 2016	0
Aviva Investors Global Services Limited		Direct		18 May 2016	51,518

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