Insider	Transaction	Type	Value	Date	Shares
Calculus Capital Ltd		Direct		22 Nov 2022	0
Redmile Group, L.L.C.		Direct		22 Nov 2022	0
Vulpes Life Science Fund		Direct		22 Nov 2022	0
Redmile Group, L.L.C.		Direct		26 Sept 2022	0
Vulpes Life Science Fund		Direct		26 Sept 2022	0
Calculus Capital Ltd		Direct		26 Sept 2022	0
Calculus Capital Ltd		Direct		23 Sept 2022	4,886,778
Adams (Sally Elizabeth)		Direct		30 Apr 2022	0
Chiplin (John C)		Direct		30 Apr 2022	0
Goodfellow (Richard Morley)		Direct		30 Apr 2022	0
Barclays Bank Plc		Direct		30 Mar 2022	0
Vulpes Life Science Fund	Bought at price 0.16 per share.	Direct	40,250	02 Mar 2022	250,000
Vulpes Life Science Fund	Bought at price 0.26 per share.	Direct	51,800	02 Nov 2021	200,000
Vulpes Life Science Fund	Bought at price 0.26 per share.	Direct	26,000	29 Oct 2021	100,000
Holloway (Clifford Michael)		Direct		28 Oct 2021	0
Goodfellow (Richard Morley)		Direct		28 Oct 2021	0
Adams (Sally Elizabeth)		Direct		28 Oct 2021	0
Chiplin (John C)		Direct		28 Oct 2021	0
Calculus Capital Ltd		Direct		27 Oct 2021	0
Redmile Group, L.L.C.		Direct		27 Oct 2021	0
Vulpes Life Science Fund		Direct		27 Oct 2021	0
Durrant (Lindy Gillian)	Sold at price 0.28 per share.	Direct	1,235,331	09 Sept 2021	4,459,681
Durrant (Lindy Gillian)	Sold at price 0.29 per share.	Direct	692,857	09 Sept 2021	2,380,952
Calculus Capital Ltd		Direct		10 Aug 2021	0
Redmile Group, L.L.C.		Direct		10 Aug 2021	0
Vulpes Life Science Fund		Direct		10 Aug 2021	0
Vulpes Life Science Fund	Bought at price 0.28 per share.	Direct	55,800	29 Jul 2021	200,000
Vulpes Life Science Fund	Bought at price 0.27 per share.	Direct	107,600	04 Jun 2021	400,000
Holloway (Clifford Michael)		Direct		30 Apr 2021	0
Vulpes Life Science Fund		Direct		30 Apr 2021	0
Durrant (Lindy Gillian)		Direct		30 Apr 2021	0
Goodfellow (Richard Morley)		Direct		30 Apr 2021	0
Adams (Sally Elizabeth)		Direct		30 Apr 2021	0
Chiplin (John C)		Direct		30 Apr 2021	0
Vulpes Life Science Fund	Bought at price 0.28 per share.	Direct	111,600	29 Apr 2021	400,000
Calculus Capital Ltd		Direct		10 Mar 2021	1,010,352
Vulpes Life Science Fund	Sold at price 0.38 per share.	Direct	150,800	18 Feb 2021	400,000
Vulpes Life Science Fund	Sold at price 0.36 per share.	Direct	450,000	17 Feb 2021	1,250,000
Vulpes Life Science Fund	Sold at price 0.33 per share.	Direct	133,600	16 Feb 2021	400,000
Vulpes Life Science Fund	Bought at price 0.15 per share.	Direct	110,250	14 Dec 2020	750,000
Vulpes Life Science Fund	Bought at price 0.14 per share.	Direct	36,079	11 Dec 2020	248,823
Holloway (Clifford Michael)	Bought at price 0.15 per share.	Direct	14,700	24 Nov 2020	100,000
Vulpes Life Science Fund	Bought at price 0.14 per share.	Direct	14,399	12 Nov 2020	100,000
Vulpes Life Science Fund	Bought at price 0.14 per share.	Direct	14,499	11 Nov 2020	100,000
Vulpes Life Science Fund	Bought at price 0.16 per share.	Direct	47,700	10 Nov 2020	300,000
Vulpes Life Science Fund	Bought at price 0.17 per share.	Direct	627,678	06 Nov 2020	3,670,635
Redmile Group, L.L.C.		Direct		02 Nov 2020	53,326,358
Vulpes Life Science Fund		Direct		02 Nov 2020	16,393,442
Redmile Group, L.L.C.		Direct		15 Oct 2020	0
Vulpes Life Science Fund		Direct		15 Oct 2020	0
Calculus Capital Ltd		Direct		15 Oct 2020	0
Calculus Capital Ltd		Direct		14 Oct 2020	0
Redmile Group, L.L.C.		Direct		14 Oct 2020	93,071,170
Redmile Group, L.L.C.		Direct		12 Aug 2020	0
Vulpes Life Science Fund	Bought at price 0.08 per share.	Direct	1,418,181	12 Aug 2020	18,181,818
Calculus Capital Ltd		Direct		12 Aug 2020	0
Vulpes Life Science Fund		Direct		05 Aug 2020	18,181,798
Vulpes Life Science Fund		Direct		22 Jul 2020	64,980
Adams (Sally Elizabeth)		Direct		30 Apr 2020	0
Chiplin (John C)		Direct		30 Apr 2020	0
Durrant (Lindy Gillian)		Direct		30 Apr 2020	0
Goodfellow (Richard Morley)		Direct		30 Apr 2020	0
Vulpes Life Science Fund	Sold at price 0.10 per share.	Direct	148,500	27 Apr 2020	1,500,000
Vulpes Life Science Fund	Sold at price 0.10 per share.	Direct	49,500	24 Apr 2020	500,000
Vulpes Life Science Fund	Bought at price 0.07 per share.	Direct	195,975	16 Dec 2019	2,925,000
Frohn (Matthew G.W.)		Direct		31 Oct 2019	0
Vulpes Life Science Fund		Direct		16 Aug 2019	0
Calculus Capital Ltd		Direct		16 Aug 2019	0
Calculus Capital Ltd		Direct		17 Jun 2019	139,103
Seneca Growth Capital VCT Plc		Direct		17 Jun 2019	100,000
Vulpes Life Science Fund		Direct		17 Jun 2019	0
Durrant (Lindy Gillian)		Direct		30 Apr 2019	0
Frohn (Matthew G.W.)		Direct		30 Apr 2019	0
Goodfellow (Richard Morley)		Direct		30 Apr 2019	0
Adams (Sally Elizabeth)		Direct		30 Apr 2019	0
Chiplin (John C)		Direct		30 Apr 2019	0
Cornish-Bowden (Katherine)		Direct		30 Apr 2019	0
City Financial Investment Company Limited		Direct		04 Mar 2019	5,000,000
Chiplin (John C)	Bought at price 0.16 per share.	Direct	392	25 Jul 2018	2,483
Chiplin (John C)	Sold at price 0.14 per share.	Direct	360	24 Jul 2018	2,483
Adams (Sally Elizabeth)	Bought at price 0.16 per share.	Direct	504	09 May 2018	3,095
Calculus Capital Ltd		Direct		09 May 2018	220,085
Cornish-Bowden (Katherine)	Bought at price 0.16 per share.	Direct	1,781	09 May 2018	10,928
Adams (Sally Elizabeth)		Direct		08 May 2018	0
Cornish-Bowden (Katherine)		Direct		08 May 2018	0
Adams (Sally Elizabeth)		Direct		30 Apr 2018	0
Chiplin (John C)		Direct		30 Apr 2018	0
Cornish-Bowden (Katherine)		Direct		30 Apr 2018	0
Durrant (Lindy Gillian)		Direct		30 Apr 2018	0
Frohn (Matthew G.W.)		Direct		30 Apr 2018	0
Goodfellow (Richard Morley)		Direct		30 Apr 2018	0
Chiplin (John C)	Bought at price 0.17 per share.	Direct	151,200	20 Apr 2018	900,000
City Financial Investment Company Limited		Direct		20 Apr 2018	0
Chiplin (John C)		Direct		18 Apr 2018	0
Seneca Growth Capital VCT Plc		Direct		18 Apr 2018	100,000
Legal & General Investment Management Ltd.		Direct		16 May 2017	0
Seneca Growth Capital VCT Plc		Direct		16 May 2017	10,127,346
Chiplin (John C)	Bought at price 0.13 per share.	Direct	134,311	16 May 2017	1,041,177
Calculus Capital Ltd		Direct		11 May 2017	1,738,662
Adams (Sally Elizabeth)		Direct		30 Apr 2017	0
Chiplin (John C)		Direct		30 Apr 2017	0
Cornish-Bowden (Katherine)		Direct		30 Apr 2017	0
Durrant (Lindy Gillian)		Direct		30 Apr 2017	0
Frohn (Matthew G.W.)		Direct		30 Apr 2017	0
Goodfellow (Richard Morley)		Direct		30 Apr 2017	0
Helium Special Situations Fund		Direct		16 Feb 2017	0
Seneca Growth Capital VCT Plc		Direct		14 Sept 2016	0
Calculus Capital Ltd		Direct		14 Sept 2016	0
Adams (Sally Elizabeth)		Direct		30 Apr 2016	0
Chiplin (John C)		Direct		30 Apr 2016	0
Cornish-Bowden (Katherine)		Direct		30 Apr 2016	0
Durrant (Lindy Gillian)		Direct		30 Apr 2016	0
Frohn (Matthew G.W.)		Direct		30 Apr 2016	0
Goodfellow (Richard Morley)		Direct		30 Apr 2016	0
Calculus Capital Ltd		Direct		05 Apr 2016	14,562,191
Oxford Technology Management Ltd		Direct		05 Apr 2016	6,683,300
Durrant (Lindy Gillian)	Bought at price 0.24 per share.	Direct	14,411	11 Mar 2016	58,823
Frohn (Matthew G.W.)	Bought at price 0.24 per share.	Direct	14,411	11 Mar 2016	58,823
Goodfellow (Richard Morley)	Bought at price 0.24 per share.	Direct	14,411	11 Mar 2016	58,823
Adams (Sally Elizabeth)	Bought at price 0.24 per share.	Direct	14,411	11 Mar 2016	58,823
Chiplin (John C)	Bought at price 0.24 per share.	Direct	14,411	11 Mar 2016	58,823
Cornish-Bowden (Katherine)	Bought at price 0.24 per share.	Direct	14,411	11 Mar 2016	58,823
Cornish-Bowden (Katherine)		Direct		09 Mar 2016	0
Oxford Technology Management Ltd	Bought at price 0.24 per share.	Direct	48,400	09 Mar 2016	200,000
Durrant (Lindy Gillian)		Direct		09 Mar 2016	1,706,960
Goodfellow (Richard Morley)		Direct		09 Mar 2016	300,000
Helfenstein (Jack G)		Direct		11 Sept 2015	0
Calculus Capital Ltd		Direct		11 Sept 2015	0
Seneca Growth Capital VCT Plc		Direct		11 Sept 2015	0
Durrant (Lindy Gillian)		Direct		30 Apr 2015	0
Goodfellow (Richard Morley)		Direct		30 Apr 2015	0
Oxford Technology Management Ltd	Decrease at price 0.39 per share.	Direct	1,715,036	25 Mar 2015	4,431,620
Calculus Capital Ltd		Direct		02 Dec 2014	2,488,313
Durrant (Lindy Gillian)		Direct		30 Apr 2014	0
Goodfellow (Richard Morley)		Direct		30 Apr 2014	0
Helfenstein (Jack G)		Direct		29 Apr 2014	0
Calculus Capital Ltd		Direct		28 Jan 2014	1,700,430
Durrant (Lindy Gillian)		Direct		10 Dec 2013	0
Goodfellow (Richard Morley)		Direct		10 Dec 2013	0
Durrant (Lindy Gillian)	Sold at price 0.48 per share.	Direct	48,400	21 Oct 2013	100,000
Goodfellow (Richard Morley)	Sold at price 0.48 per share.	Direct	48,400	21 Oct 2013	100,000
Calculus Capital Ltd		Direct		01 Oct 2013	909,626
Helium Special Situations Fund		Direct		08 Aug 2013	950,000
Calculus Capital Ltd		Direct		02 Aug 2013	19,465,220
Allen (Peter)	Bought at price 0.51 per share.	Direct	25,350	22 Jul 2013	50,000
Cornish-Bowden (Katherine)	Bought at price 0.49 per share.	Direct	22,095	22 Jul 2013	45,000
Evans (David Eric)	Bought at price 0.49 per share.	Direct	14,730	22 Jul 2013	30,000
Helfenstein (Jack G)		Direct		04 Jul 2013	0
Durrant (Lindy Gillian)		Direct		30 Apr 2013	0
Goodfellow (Richard Morley)		Direct		30 Apr 2013	0

NIKKEI 22538,197.23-76.82(-0.20%)

HANG SENG17,930.86+167.83(+0.94%)

CRUDE OIL79.32+0.32(+0.41%)

GOLD FUTURES2,334.30+23.30(+1.01%)

DOW37,903.29+87.37(+0.23%)

Bitcoin GBP45,739.50-1,869.83(-3.93%)

Family finances

Scancell Holdings plc (SCNLF)

Insider transactions

Insider transactions reported - last two years

NIKKEI 225
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HANG SENG
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CRUDE OIL
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GOLD FUTURES
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DOW
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Bitcoin GBP
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