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BUZZ-U.S. STOCKS ON THE MOVE-Galectin, Monsanto, Portugal Telecom

(Adds Portugal Telecom, Galectin, Karyopharm; Updates Alkermes, Eli Lilly, Keurig, Monsanto, Supervalu (NYSE: SVU - news) ) (For faster updates on individual market-movers, Eikon users please use search string "STXBZ US"; for the Day Ahead newsletter, http://link.reuters.com/mex49s; for the Morning News Call newsletter, http://link.reuters.com/nex49s)

U.S. stock index futures extended sharp gains on Wednesday after strong ADP employment data. Dow Jones industrial average futures were up 0.86 percent at 17,439, S&P 500 futures were up 0.88 percent at 2,012 and Nasdaq 100 futures were up 0.73 percent at 4,132.25.

** PORTUGAL TELECOM SGPS SA, Tuesday close $0.95, -6.32 pct premarket

Shares (Dusseldorf: DI6.DU - news) in Portugal Telecom slumped 20 percent to all-time lows on Wednesday as investors dumped the stock after authorities searched its offices on suspicions of fraud.

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** GALECTIN THERAPEUTICS INC (NasdaqCM: GALT - news) , Tuesday close $3.23, +37.46 pct premarket

The drug developer said final results of the early-stage trial of its GR-MD-02 in fatty liver disease, or nonalcoholic steatohepatitis with advanced fibrosis, demonstrated that the drug was safe and well tolerated after multiple doses.

** KARYOPHARM THERAPEUTICS INC (NasdaqGS: KPTI - news) , Tuesday close $33.47, -2.75 pct premarket

The drug developer priced its public offering of 3 million shares at $33 each, a discount of 1.4 percent to stock's Tuesday closing. Offering represents about 9 percent of Karyopharm's outstanding shares as of Jan. 6, according to Thomson Reuters data.

** MONSANTO CO, Tuesday close $116.25, +0.97 pct premarket

The world's largest seed company said profits dropped 34 percent in the first quarter compared with a year ago, due in part to lower planted corn acres in South America and a shift in timing of some sales.

** SUPERVALU INC, Tuesday close $9.19, +4.46 pct premarket

The supermarket chain reported third-quarter adjusted profit and sales above analysts' estimates as comparable sales rise at its Save (Milan: SAVE.MI - news) -A-Lot stores. sales at Save-A-Lot stores rose 6.9 percent in third quarter. Analysts expected 4.8 percent rise, according to Consensus Metrix poll.

** ALKERMES PLC (NasdaqGS: ALKS - news) , Tuesday close $60.93, +3.40 pct premarket

Alkermes said its experimental drug to treat schizophrenia met the main goal in a mid-stage trial. The drug, codenamed ALKS 3831, is a combination of samidorphan and the antipsychotic olanzapine.

** KEURIG GREEN MOUNTAIN INC (Xetra: A1XFME - news) , Tuesday close $127.19, +2.70 pct premarket

** SNAPPLE GROUP INC, Tuesday close $71.48, -100.00 pct premarket

The maker of the K-Cup single-serve coffee pod, will sell Dr Pepper Snapple Group's soda pods for its at-home cold beverage system, Keurig Cold, expected to be launched this year. Dr Pepper's beverage brands include Snapple, 7-Up and Schweppes.

** ELI LILLY AND CO, Tuesday close $69.72, +1.19 pct premarket

The drugmaker, which has been battered in the past three years by competition from generics, forecast 2015 earnings and revenue just shy of Wall Street expectations. Lilly, which is betting on its rejuvenated pipeline of drugs, particularly for diabetes, oncology and animal health, forecast adjusted 2015 earnings of $3.10 to $3.20 per share.

** BOEING CO (NYSE: BA - news) , Tuesday close $127.53, +1.38 pct premarket

Airbus Group beat the planemaker in aircraft orders in 2014, maintaining a lead in new business despite lagging in deliveries, a person familiar with the matter said on Tuesday.

** ZAFGEN INC (NasdaqGS: ZFGN - news) , Tuesday close $32.17, +1.80 pct premarket

The company said a mid-stage study showed its experimental drug reduced weight in patients obese due to damage to a part of the brain. The drug, beloranib, was tested against a placebo in 14 adults with obesity resulting from damage to the hypothalamus following surgery to remove a kind of brain tumor.

** SIRIUS XM HOLDINGS, Tuesday close $3.35, +1.79 pct premarket

The satellite radio service company said it would beat its 2014 revenue forecast of $4.15 billion after net subscriber additions exceeded expectations. The company reported about 1.8 million net subscriber additions for the year, above its increased forecast of 1.5 million.

** AVEO PHARMACEUTICALS INC (NasdaqGS: AVEO - news) , Tuesday close $0.84

The company doing business as Aveo Oncology said it planned to cut two-thirds of its workforce, or 40 positions, as part of a restructuring that includes the departure of Chief Scientific Officer Jeno Gyuris.

** PIONEER NATURAL RESOURCES (NYSE: PXD - news) , Tuesday close $139.46, +1.27 pct premarket

Topeka Capital cuts its target price to $158 from $200 on the oil and gas producer's stock after the company said it has restructured most of its 2015 hedge position to protect against further falls in oil prices.

** KALOBIOS PHARMACEUTICALS INC (NasdaqGM: KBIO - news) , Tuesday close $1.83, -67.76 pct premarket

KaloBios Pharmaceuticals said it would discontinue the development of its drug for lung infections in cystic fibrosis patients after it failed in a mid-stage study.

** J.C. PENNEY CO INC, Tuesday close $6.56, +20.88 pct premarket

The department store operator said same-store sales rose 3.7 percent in November and December, boosting its shares and offering a glimpse of what is expected to be the best holiday season for retailers since.

** VERIZON COMMUNICATIONS INC (Xetra: 868402 - news) , Tuesday close $47.04, -0.21 pct premarket

** AOL INC (NYSE: AOL - news) , Tuesday close $46.25, +0.02 pct premarket

Verizon Communications CEO Lowell McAdam said the company was not planning any major acquisitions, following a report that Verizon (NYSE: VZ - news) had approached AOL for a potential deal.

** FIAT CHRYSLER AUTOMOBILES NV, Tuesday close $11.59, +0.78 pct premarket

Jeep, the SUV brand that is key to Fiat Chrysler's global expansion plans, narrowly met its goal of selling one million vehicles in 2014, the Jeep brand chief said on Tuesday.

** ROYAL DUTCH SHELL (Xetra: R6C1.DE - news) , Tuesday close $63.02, +0.46 pct premarket

The Anglo-Dutch oil company will pay out 55 million pounds ($83.4 million) in compensation for two oil spills in Nigeria in 2008 after agreeing a settlement with the affected community.

** INTEL CORP, Tuesday close $35.28, +1.19 pct premarket

Chief Executive Brian Krzanich showed off a computer built into a jacket button and a wristband that transforms into a selfie-snapping flying camera, as the chipmaker extended its push into smart wearable gadgets.

** APPLE INC (NasdaqGS: AAPL - news) , Tuesday close $106.26, +0.81 pct premarket

Audio equipment maker Monster LLC has sued Beats Electronics LLC, owned by Apple, over alleged "fraud and deceit" in the way Beats acquired control of the rights to the popular "Beats by Dr. Dre" headphones.

** MICRON TECHNOLOGY INC (NasdaqGS: MU - news) , Tuesday close $32.87, -3.07 pct premarket

JP Morgan cut price target to $40 from $45, while Nomura cut it to $40 from $41; median price target is $42. Micron's memory chip output will fall as company plans to convert capacity and it also expects selling price for its chips to fall in February quarter, JP Morgan analysts wrote in note.

The memory chipmaker gave a quarterly revenue forecast on Tuesday that missed Wall Street's expectations, hurt by an output drop as it upgrades DRAM production lines, and its shares fell.

** CONTINENTAL RESOURCES INC (NYSE: CLR - news) , Tuesday close $33.59, +2.11 pct premarket

CEO Harold Hamm, embroiled in a bitter divorce, offered to pay his former wife $974.8 million, but she rejected a hand-written check, lawyers for both sides said on Tuesday.

** AMAZON.COM INC, Tuesday close $295.29, +0.58 pct premarket

Crowdsourced fundraising site Kickstarter has dropped Amazon.com (NasdaqGS: AMZN - news) as its global payments processor in favor of Stripe, the fast-growing startup used by Twitter Inc (Xetra: A1W6XZ - news) , Facebook Inc and Apple Inc.

The switch comes as the Internet retailer begins to move clients from its customizable checkout service to an Amazon-branded one. (Compiled by Lehar Maan; Editing by Joyjeet Das)